PYRROLNITRIN AND HYDROGEN CYANIDE PRODUCTION BY PSEUDOMONAS CHLORORAPHIS STRAIN PA23 EXHIBITS NEMATICIDAL AND REPELLENT ACTIVITY AGAINST CAENORHABDITIS ELEGANS.

Pyrrolnitrin and Hydrogen Cyanide Production by Pseudomonas chlororaphis Strain PA23 Exhibits Nematicidal and Repellent Activity against Caenorhabditis elegans.

Pseudomonas chlororaphis strain PA23 is a biocontrol agent able to suppress growth of the fungal pathogen Sclerotinia sclerotiorum.This bacterium produces an arsenal of exometabolites including pyrrolnitrin (PRN), phenazine (PHZ), hydrogen cyanide (HCN), and degradative enzymes.Production of these compounds is controlled at both the transcriptional

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Transcriptomics-informed pharmacology identifies epigenetic and cell cycle regulators that enhance AAV production

Recombinant adeno-associated virus (rAAV) is a widely used viral vector for gene therapy.However, these vectors have limited availability due to manufacturing challenges with productivity and quality.These challenges can be addressed by better understanding the mechanisms that influence cellular responses during rAAV production.In this study, we ai

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Type-B anomaly matching and the 6D (2,0) theory

Abstract We study type-B conformal anomalies associated with 1 2 $$ rac{1}{2} $$ -BPS Coulomb-branch operators in 4D N $$ mathcal{N} $$ = 2 superconformal field theories.When the vacuum preserves the conformal symmetry these anomalies coincide with the two-point function coefficients in the Coulomb-branch chiral ring.They are non-trivial functions

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